PREVENTION WITH DESORGESTREL OF ENDOMETRIOUS CYSTS RECURRENCE AFTER SURGICAL TREATMENT

  • Eduard Crauciuc
  • Diana Popovici
  • Alia Sindilar
  • Ovidiu Toma
  • Dragos Crauciuc
Keywords: infertility

Abstract

Currently, endometriosis is an important public health issue due to the increasing number of cases and the risk of developing ovarian and endometrial tumours(10% of ovarian endometrial carcinomas are associated with uterine endometrioid carcinomas), which has led to increased research into the mechanisms of appearance and progression of this condition.Although endometriosis is considered a benign chronic disease, it can show an invasive character causing severe symptoms. Endometriosis has an increasing incidence, affecting 2% of the general population, being the third gynecological cause of infertility, chronic pelvic pain, dyspareunia and dysmenorrhea. Endometriosis affects 7-15% of women of childbearing age, with 25-30% of sterility cases having a significant social impact. Endometriomas are difficult to excise due to vascularization and increased adhesion of the cyst wall. Surgical treatment of endometriosis is effective in the short term. Surgery most often reduces ovarian reserve. The rate of recurrence after surgery can be reduced with the help of menstrual suppression medications such as hormonal contraceptives. Desogestrel treatment improves intraoperative conditions mainly by reducing bleeding and increasing laxity between cyst coat and normal ovarian tissue.

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Published
2018-11-08
How to Cite
Crauciuc, E., Popovici, D., Sindilar, A., Toma, O., & Crauciuc, D. (2018). PREVENTION WITH DESORGESTREL OF ENDOMETRIOUS CYSTS RECURRENCE AFTER SURGICAL TREATMENT. Journal of Experimental and Molecular Biology, 19(3), 67-72. Retrieved from http://www.jemb.bio.uaic.ro/index.php/jemb/article/view/22
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